Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.
Researchers are abandoning the concept of a list of genes sequenced from a single individual, instead aiming for a way to describe all the genetic variation within a species.
This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.
Meet some of the people featured in the December 2016 issue of The Scientist.
The awesome architecture of the gateways to the nucleus
The importance of science innovation, publishing and gender, and more
A family’s collection of antique microscope slides became a trove of genetic information about the eradicated European malaria pathogen.
Scientists are enlisting the help of pigeons, parrots, crows, jays, and other species to disprove the notion that human cognitive abilities are beyond those of other animals.
Researchers discover diverse communities of invertebrates inhabiting the water-filled tracks of elephants in Uganda.
Certain microbes express genes in a methane-production pathway, offering an explanation for puzzlingly high levels of the gas in some lakes.
Sorting out which data sets are clinical-grade is key to helping patients.
Engineered circuits detect endogenous transcription factors to drive cellular outputs.
Cells with the best traction on a substrate pull their neighbors toward firmer ground.
Spruce and pine and have relied on similar genetic toolkits for climate adaptation despite millions of years of evolution.
Different assays lead to opposing conclusions on bacterial spores’ requirements during germination.
Applying physics, chemistry, and cell biology, Satyajit Mayor seeks to understand how cell membranes work.
The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.
Sequencing and gene-editing advances make tracing a cell’s journey throughout development easier than ever.
Improvements in instruments and statistical tools allow the capture and analysis of large data sets.
Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.
Using precision genome editing to treat or prevent human disease may require several leaps of faith.
In 1992, advancements in microscopy zoomed in on the precise architecture of the complex, including unforeseen structural repetition in two halves of the ring.