News & Opinion

How Gaining and Losing Weight Affects the Body
How Gaining and Losing Weight Affects the Body

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

Learning Opens the Genome
Learning Opens the Genome

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

Primary Cilia in Neurons Linked to Obesity
Primary Cilia in Neurons Linked to Obesity

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes.