Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.
Sequencing has gone from a laborious manual task costing thousands of dollars to a quick and cheap practice that is standard for many laboratories.
From confocal fluorescence microscopy to super-resolution and live 3-D imaging, microscopes have changed rapidly since 1986.
Imaging and manipulating the brain has come a long way from electrodes and the patch clamp, though such traditional tools remain essential.
Advances in genetic manipulation have simplified the once daunting task of rewriting a gene.
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Bacteria inhabit most tissues in the human body, and genes from some of these microbes have made their way to the human genome. Could this genetic transfer contribute to diseases such as cancer?
Meet some of the people featured in the October 2016 issue of The Scientist
Celebrating 30 years and a resurrection
Roger Tsien R.I.P., predatory publishing, and diversity in science
A nude birder and an Australian zoo owner are competing to set the new bar for the number of species spotted in a single year.
From mouth pipetting to automated liquid handling, life-science labs have gotten much safer over the past three decades.
A molecular biologist ventures into entomology to use genetically modified ants as laboratory models of behavioral epigenetics.
Genetic analyses lay to rest conspiracy theories about death of Belgian King Albert I, who lost his life in a rock climbing accident more than 80 years ago.
A patent dispute over gene editing highlights the need for scientists to agree on IP ownership early.
Four independent research groups develop techniques for visualizing peptide production in living cells.
Some ciliates use the same trio of nucleotides to code for an amino acid and to stop translation.
Photon emissions in the brain are red-shifted in more-intelligent species, though scientists dispute what that means.
NSAIDs reduce this "parainflammation," hinting at how they help lower cancer risk.
George Church has consistently positioned himself at genomics’ leading edge.
Founder and CEO, Curable; Adjunct Assistant Professor, University of Pittsburgh. Age: 35
Using the technique to study how RNA, DNA, lipids, and small molecules interact with proteins
As the importance of genomic copy number variations for health and disease becomes clearer, researchers are creating new ways to detect these changes in the genome.
Companies focused on developing treatments for dogs, cats, and horses are bringing a diverse array of products to the pet medicine market.
Are leading researchers driven more by the quest for knowledge or the pursuit of fame?
Tweaks to a transformation protocol in 1986 cemented the little plant's mighty role in plant genetics research.