Modus Operandi

These engineered “cells” were made from the secretions and membranes of human mesenchymal stem cells.

Incorporating light-controlled dimerization domains into kinases provides tight regulation of these enzymes.

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

A test tube-based genome-labeling technique has been brought under the microscope.

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.  

Four independent research groups develop techniques for visualizing peptide production in living cells.

Scientists generate new protein-protein interactions at an impressive PACE.

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.